Brief Apnea and Hypoventilation Reduces Seizure Duration and Shifts Seizure Location for Several Hours in a Model of Severe Traumatic Brain Injury.
Frances Rodriguez Lara, Praneel Sunkavalli, Michael Mikaelian, Bryan Golemb, David Y Chung, Ann-Christine Duhaime, Kevin Staley, and Beth Costine-Bartell.
Epilepsia May 16, 2024
Developmental regulation of matrix metalloproteinases in response to multi-factorial, severe TBI injuries during immaturity.
Alexandra Hochstetler, George Price, Amy Baohan, Melissa Li, Frances Rodriguez Lara, Josephine Lok J, Beth Costine-Bartell.
Developmental Neuroscience January 8, 2024
Backpack-mediated anti-inflammatory macrophage cell therapy for the treatment of traumatic brain injury.
Neha Kapate, Rick Liao, Ryan Luke Sodemann, Tawny Stinson, Supriya Prakash, Ninad Kumbhojkar, Vineeth Chandran Suja, Lily Li-Wen Wang, Mikayla Flanz, Rohan Rajeev, Dania Villafuerte, Suyog Shaha, Morgan Janes, Kyung Soo Park, Michael Dunne, Bryan Golemb, Alexander Hone, Kolade Adebowale, John Clegg, Andrea Slate, Declan McGuone, Beth Costine-Bartell, Samir Mitragotri.
PNAS Nexus. December 13, 2023. 3(1):434.
2-Photon imaging of fluorescent proteins in living swine.
Beth Costine-Bartell, Luis Martinez Ramirez**, Kieran Normoyle, Tawny Stinson, Kevin Staley, and Kyle Lillis.
Scientific Reports. August 29 2023.13(1):14158
Robust, long-term video EEG monitoring in a porcine model of post-traumatic epilepsy.
Luis Martinez Ramirez, Andrea Slate, George Price, Ann-Christine Duhaime, Kevin Staley, and Beth Costine-Bartell.
eNeuro June 2022 10;9(4)
A perfect storm: The distribution of tissue damage depends on seizure duration, hemorrhage, and developmental stage in a gyrencephalic, multi-factorial, severe traumatic brain injury model.
Beth Costine-Bartell, George Price, John Shen, Declan McGuone, Kevin Staley, and Ann-Christine Duhaime.
Neurobiology of Disease. 2021. 154:105334.
Development of a Model of Hemispheric Hypodensity (“Big Black Brain”).
Beth Costine-Bartell, Declan McGuone, George Price, Eleanor Crawford, Kristen Keeley, Jennifer Munoz- Pareja, Carter Dodge, Kevin Staley, and Ann-Christine Duhaime.
Journal of Neurotrauma. 2019. 36 (5): 815-833.
Infant with Seizures with Unknown Etiology
Beth A Costine and Ann-Christine Duhaime. Pediatric Neurosurgery Casebook. Selden & Baird, editors
Oxford University Press.
Neuroblast Distribution after Cortical Impact is Influenced by White Matter Injury in the Immature Gyrencephalic Brain.
Sabrina Taylor, Colin Smith, Kristen Keeley, Declan McGuone, Carter Dodge, Ann-Christine Duhaime, and Beth Costine.
Frontiers in Neuroscience 2016. 10:387.
The Subventricular Zone in the Immature Piglet Brain: Anatomy and Exodus of Neuroblasts into White Matter after Traumatic Brain Injury.
Beth Costine, Symeon Missios, Sabrina Taylor, Declan McGuone, Colin Smith, Carter Dodge, Brent Harris, and Ann-Christine Duhaime
Developmental Neuroscience 2015 February 10 37 (2): 115–130
Neuronal specific enolase, but not S100B nor myelin basic protein, increases in peripheral blood corresponding to lesion volume after cortical impact in piglets.
BA Costine, Patricia Quebeda-Clerkin, Carter Dodge, Brent Harris, Simon Hillier, and Ann-Christine Duhaime.
Journal of Neurotrauma. 2012. 20;29(17):2689-95
Full list of publications.
The MGH Brain Trauma Lab
MGH Neurosciences
Department of Neurosurgery, Massachusetts General Hospital
Department of Neurosurgery, Harvard Medical School
